ADX-102 (Reproxalap;NS-2) Datasheet DC Chemicals

Description	ADX-102 (Reproxalap, NS-2) is a novel small molecule immunomodulator that covalently binds aldehydes including malondialdehyde and 4-hydroxynonenal, which have been shown to mediate inflammatory pain; DX-102 is a promising agent for the treatment of dry eye disease.
Cat.No	DC11097
Name	ADX-102 (Reproxalap;NS-2)

Chemical Properties

CAS	916056-79-6
Formula	C12H13CLN2O
MW	236.699
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Susan Macdonald, et al. ADX-102, a novel aldehyde trap, reduces nociceptive behavior in mouse models of carrageenan and CFA induced pain. [2]. Reproxalap Phase 2b Dry Eye Disease Results.

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