AF64394 Datasheet DC Chemicals

Description	AF64394 is a potent, selective GPR3 inverse agonist with pIC50 of 7.3, displays >100-fold selectivity over GPR6 and GPR12.
Cat.No	DC11170
Name	AF64394

Chemical Properties

CAS	1637300-25-4
Formula	C21H20CLN5O
MW	393.8694
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Jensen T, et al. The identification of GPR3 inverse agonist AF64394; the first small molecule inhibitor of GPR3 receptor function. Bioorg Med Chem Lett. 2014 Nov 15;24(22):5195-8.

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