Diptoindonesin G Datasheet DC Chemicals

Description	Dip G is a natural compound, novel chemical probe reciprocally stabilizes ERβ and destabilizes ERα in breast cancer cells; targets CHIP ubiquitin E3 ligase to modulate ER protein stability, enhances the transcription and anti-proliferative activities of ERβ, while attenuating the transcription and proliferative effects of ERα; the first small molecule that can restore the balance of ERα and ERβ.
Cat.No	DC11658
Name	Diptoindonesin G

Chemical Properties

CAS	1190948-58-3
Formula	C21H12O6
MW	360.321
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

References 1. Zhao Z, et al. Chem Biol. 2015 Dec 17;22(12):1608-21. 2. Juliawaty LD, et al. Nat Prod Commun. 2009 Jul; 4(7):947-50. 3. Gao J, et al. Cell Death Dis. 2017 May 4;8(5):e2765. View Related Products by Target Estrogen Receptor/ERR

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