AZD-7986(Brensocatib) Datasheet DC Chemicals

Description	AZD-7986(Brensocatib) is a highly potent, reversible, and selective DPP1 inhibitor with enzyme and cell pIC50 of 8.4.
Cat.No	DC11723
Name	AZD-7986(Brensocatib)

Chemical Properties

CAS	1802148-05-5
Formula	C23H24N4O4
MW	420.469
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Doyle K, et al. Discovery of Second Generation Reversible Covalent DPP1 Inhibitors Leading to an Oxazepane Amidoacetonitrile Based Clinical Candidate (AZD7986). J Med Chem. 2016 Oct 27;59(20):9457-9472

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