BAY-8040 (R) Datasheet DC Chemicals

Description	Bay-8040 is a potent, selective human neutrophil elastase (HNE) inhibitor with IC50 of 28 nM; displays no significant inhibition toward 68 other pharmacologically relevant targets (>10 uM), and a panel of related serine proteases; shows in vivo efficacy with regard to decreasing cardiac remodeling and amelioration of cardiac function in monocrotaline-induced rat model for pulmonary arterial hypertension.
Cat.No	DC11857
Name	BAY-8040 (R)

Chemical Properties

CAS	1194453-23-0
Formula	C21H16F3N5O2
MW	427.379
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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