JP-153 Datasheet DC Chemicals

Description	JP-153 (JP153) is a novel small molecule targets the Src-FAK-Paxillin signaling, inhibits Src-dependent phosphorylation of paxillin (Y118) and downstream activation of Akt (S473) in RECs; potently inhibits VEGF-induced proliferation and migration, inhibits retinal neovascularization in the murine oxygen-induced retinopathy model.
Cat.No	DC11954
Name	JP-153

Chemical Properties

CAS	1802937-26-3
Formula	C21H19NO5
MW	365.385
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

References 1. Toutounchian JJ, et al. Mol Pharmacol. 2017 Jan;91(1):1-13. View Related Products by Target Src

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