PI3K/mTOR Inhibitor-2 Datasheet DC Chemicals
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Cat.No DC20036
Name PI3K/mTOR Inhibitor-2

Chemical Properties

CAS 1848242-58-9
Formula C20H13CLF2N4O4S
MW 478.86
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.:1848242-58-9
Product Name:
Synonyms:
EINEC:
Molecular Formula:C20H13ClF2N4O4S
Molecular Weight:478.86
Target: PI3Kα:3.4 nM (IC50) PI3Kβ:34 nM (IC50) PI3Kδ:16 nM (IC50) PI3Kγ:1 nM (IC50) mTOR:4.7 nM (IC50)
In Vivo
In Vitro
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Yu T, et al. Discovery of Pyridopyrimidinones as Potent and Orally Active Dual Inhibitors of PI3K/mTOR. ACS Med Chem Lett. 2018 Feb 27;9(3):256-261.
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