PI3K/mTOR Inhibitor-2 Datasheet DC Chemicals

Description	PI3K/mTOR Inhibitor-2 is a potent dual pan-PI3K/mTOR inhibitor with IC50s of 3.4/34/16/1 nM for PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ and 4.7 nM for mTOR. Antitumor activity.
Cat.No	DC20036
Name	PI3K/mTOR Inhibitor-2

Chemical Properties

CAS	1848242-58-9
Formula	C20H13CLF2N4O4S
MW	478.86
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Yu T, et al. Discovery of Pyridopyrimidinones as Potent and Orally Active Dual Inhibitors of PI3K/mTOR. ACS Med Chem Lett. 2018 Feb 27;9(3):256-261.

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