Kira8 Datasheet DC Chemicals

Description	Kira8 is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α’s RNase.
Cat.No	DC20111
Name	Kira8

Chemical Properties

CAS	1630086-20-2
Formula	C31H29CLN6O3S
MW	601.12
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Morita S, et al. Targeting ABL-IRE1α Signaling Spares ER-Stressed Pancreatic β Cells to Reverse Autoimmune Diabetes. Cell Metab. 2017 Apr 4;25(4):883-897.e8.

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