NRX2663 Datasheet DC Chemicals

Description	NRX-2663 is an enhancer of the interaction between β-catenin, and its cognate E3 ligase, SCFβ-TrCP. NRX-2663 enhances the binding of β-catenin peptide for β-TrCP with an EC50 of 22.9 µM and a Kd of 54.8 nM[1].
Cat.No	DC20250
Name	NRX2663

Chemical Properties

CAS	2763260-34-8
Formula	C20H13F3N2O5
MW	418.32
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

References

[1]. Kyle R Simonetta, et al. Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nat Commun. 2019 Mar 29;10(1):1402.

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