ANTISAUVAGINE-30 Datasheet DC Chemicals
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Cat.No DC20309
Name ANTISAUVAGINE-30

Chemical Properties

CAS 220673-95-0
Formula C161H273N47O47S
MW 3651.24201999998
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：220673-95-0
Product Name：ANTISAUVAGINE-30
Synonyms：ANTISAUVAGINE-30;D-PHE-HIS-LEU-LEU-ARG-LYS-MET-ILE-GLU-ILE-GLU-LYS-GLN-GLU-LYS-GLU-LYS-GLN-GLN-ALA-ALA-ASN-ASN-ARG-LEU-LEU-LEU-ASP-THR-ILE-NH2;(D-PHE11,HIS12)-SAUVAGINE (11-40);(D-PHE11,HIS12)-SAUVAGINE (11-40) TRIFLUOROACETATE SALT;H-D-PHE-HIS-LEU-LEU-ARG-LYS-MET-ILE-GLU-ILE-GLU-LYS-GLN-GLU-LYS-GLU-LYS-GLN-GLN-ALA-ALA-ASN-ASN-ARG-LEU-LEU-LEU-ASP-THE-ILE-OH;H-D-PHE-HIS-LEU-LEU-ARG-LYS-MET-ILE-GLU-ILE-GLU-LYS-GLN-GLU-LYS-GLU-LYS-GLN-GLN-ALA-ALA-ASN-ASN-ARG-LEU-LEU-LEU-ASP-THR-ILE-NH2;M.W. 3650.29 C161H274N48O46S;(D-Phe??00His??)-Sauvagine(11-40);(D-Phe11,His12)-Sauvagine (11-40), Antisauvagine-30;11-D-Phenylalanine-12-L-histidine-11-40-sauvagin
EINECS:
Molecular Formula：C161H273N47O47S
Molecular Weight：3651.24201999998
Target: Kd: 1.4 nM (mouse CRF2β) ;Kd: 153.6 nM (rat CRF1)[1]
In Vivo
In Vitro
Kinase Assay
Cell Assay
Animal Administration

References

[1]. O Brauns, et al. Pharmacological and chemical properties of astressin, antisauvagine-30 and alpha-helCRF: significance for behavioral experiments. Neuropharmacology. 2001 Sep;41(4):507-16. [2]. Farahnaz Sananbenesi, et al. Mitogen-activated protein kinase signaling in the hippocampus and its modulation by corticotropin-releasing factor receptor 2: a possible link between stress and fear memory. J Neurosci
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