LXRβ agonist 17 Datasheet DC Chemicals

Description	LXRβ agonist 17 is a novel, potent, orally active liver X receptor β (LXRβ) agonist with Ki/EC50 of 3/21 nM, displays 27-fold selectivity over LXRα; also exhibits excellent selectivity against other nuclear hormone receptors (>3,000-fold); induces the expression of LXR target genes in vitro and in vivo.
Cat.No	DC20439
Name	LXRβ agonist 17

Chemical Properties

CAS	1878259-00-7
Formula	C21H27F3N4O4S
MW	488.52369427681
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

References 1. Zheng Y, et al. J Med Chem. 2016 Apr 14;59(7):3264-71. View Related Products by Target Liver X Receptor (LXR)

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