Asciminib Datasheet DC Chemicals

Description	Asciminib (ABL-001) is a potent and selective allosteric ABL1 inhibitor with IC50 of 0.25 nM in BCR–ABL1-transformed BaF3 cells.
Cat.No	DC20622
Name	Asciminib

Chemical Properties

CAS	1492952-76-7
Formula	C20H18CLF2N5O3
MW	449.8428
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Wylie AA, et al. The allosteric inhibitor ABL001 enables dual targeting of BCR-ABL1. Nature. 2017 Mar 30;543(7647):733-737.

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