FN1-8 Datasheet DC Chemicals

Description	FN1-8 is a novel, synthetic small molecule that efficiently interferes with Gli/TAF9 interaction and downregulate Gli/TAF9-dependent transcriptional activity (at 15 uM); inhibits non-canonical Gli activation and acts downstream of the canonical Hh pathway; suppresses cancer cell proliferation in vitro and inhibits tumor growth in vivo.
Cat.No	DC21050
Name	FN1-8

Chemical Properties

CAS	1419258-63-1
Formula	C29H25N3O2
MW	447.527706861496
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

1. Bosco-Clément G, et al. Oncogene. 2014 Apr 17;33(16):2087-97. 2. He B, et al. US Patent No. 7714014. 2010

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