HJC0197 Datasheet DC Chemicals
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Cat.No DC21116
Name HJC0197

Chemical Properties

CAS 1383539-73-8
Formula C19H21N3OS
MW 339.45
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：1383539-73-8
Product Name：4-cyclopentyl-2-((2,5-dimethylbenzyl)thio)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile
Synonyms：HJC0197;HJC-0197;HJC 0197
EINECS:
Molecular Formula：C19H21N3OS
Molecular Weight：339.45
Target:
In Vivo
In Vitro HJC0197 (25 μM) also inhibits Epac1-mediated Rap1-GDP exchange activity at 25 μM in the presence of equal concentration of cAMP[1]
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Chen H, et al. 5-Cyano-6-oxo-1,6-dihydro-pyrimidines as potent antagonists targeting exchange proteins directly activated by cAMP. Bioorg Med Chem Lett. 2012 Jun 15;22(12):4038-43.
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