Apicidin Datasheet DC Chemicals
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Cat.No DC21448
Name Apicidin

Chemical Properties

CAS 183506-66-3
Formula C33H47N5O7
MW 625.755588769913
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：183506-66-3
Product Name：Cyclo[(2S)-2-amino-8-oxodecanoyl-1-methoxy-L-tryptophyl-L-isoleucyl-(2R)-2-piperidinecarbonyl]
Synonyms：Cyclo[(2S)-2-amino-8-oxodecanoyl-1-methoxy-L-tryptophyl-L-isoleucyl-(2R)-2-piperidinecarbonyl];Apicidin;(3S,6S,9S,12R)-3-[(2S)-butan-2-yl]-6-[(1-methoxyindol-3-yl)methyl]-9-(6-oxooctyl)-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-tetrone;Acipidin;OSI-2040;APICIDIN;OSI 2040;Ccris 9163;Apicidin Ia;APICIDIN, FUSARIUM SPECIES;CYCLO-[L-(2-AMINO-8-OXODECANOYL)-L-(N-METHOXYTRYPTOPHAN)-L-ISOLEUCYL-D-PIPECOLINYL;CYCLO-L-(2-AMINO-8-OXODEACANOYL)-L-(N-METHOXY-TRYPTOPHAN)-L-ISOLEUCYL-D-PIPECOLINYL;Cyclo(8-oxo-L-2-aMinodecanoyl-1-Methoxy-L-tryptophyl-L-isoleucyl- D-2-piperidinecarbonyl);Cyclo[(2S)-2-aMino-8-oxodecanoyl-1-Methoxy-L-tryptophyl-L-isoleucyl-(2R)-2-piperidinecarbonyl];CYCLO[(2S)-2-AMINO-8-OXODECANOYL-1-METHOXY-L-TRYPTOPHYL-L-ISOLEUCYL-(2R)-2-PIPERIDINEXCARBONYL]
EINEC:
Molecular Formula：C33H47N5O7
Molecular Weight：625.755588769913
Target: HDAC[1]
In Vivo
In Vitro
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Han JW, et al. Apicidin, a histone deacetylase inhibitor, inhibits proliferation of tumor cells via induction of p21WAF1/Cip1 and gelsolin. Cancer Res. 2000 Nov 1;60(21):6068-74.
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