Pax2 inhibitor EG1 Datasheet DC Chemicals

Description	Pax2 inhibitor EG1 (EG1) is a potent, small molecule inhibitor of Pax2 mediated transcription activation, effectively blocks Pax2 activity and DNA binding with Kd of 1.35-1.5 uM; inhibits Pax2 mediated expression with IC50 of 10 uM, and inhibits proliferation of Pax2 positive renal and ovarian cancer cell lines but has little effect on Pax2 negative cancer cells; inhibits embryonic kidney development.
Cat.No	DC21457
Name	Pax2 inhibitor EG1

Chemical Properties

CAS	693241-54-2
Formula	C22H18N2O5
MW	390.38
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

References 1. Grimley E, et al. ACS Chem Biol. 2017 Mar 17;12(3):724-734. View Related Products by Target Other Targets

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