PFM01 Datasheet DC Chemicals

Description	PFM01 (SML1735) is a small molecule that specifically inhibits endonuclease, but not exonuclease activity of MRE11, inhibits dsDNA end resection in A549 cells with IC50 of 50-75 uM, blocks the ssDNA-binding path toward the catalytic metal ions and disrupt
Cat.No	DC21665
Name	PFM01

Chemical Properties

CAS	1558598-41-6
Formula	C14H15NO2S2
MW	293.399
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

References 1. Shibata A, et al. Mol Cell. 2014 Jan 9;53(1):7-18. 2. Hengel SR, et al. Cell Chem Biol. 2017 Sep 21;24(9):1101-1119. View Related Products by Target DNA Repair Protein

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