VU 0465350 Datasheet DC Chemicals

Description	VU 0465350 is a potent, specific BMP receptor activin receptor-like kinase 3 (ALK3) antaognist with Ki of 92.3 nM; shows no activity for ALK2/4/5, also shows affinity for TGFBR2, VEGFR2 and AMPK; blocks SMAD phosphorylation in vitro and in vivo, and enhances liver regeneration after partial hepatectomy.
Cat.No	DC21807
Name	VU 0465350

Chemical Properties

CAS	1414843-61-0
Formula	C19H18N4O
MW	318.38
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

References 1. Tsugawa D, et al. J Pharmacol Exp Ther. 2014 Dec;351(3):549-58. View Related Products by Target TGF beta Receptor (TGFBR)

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