AP20187 Datasheet DC Chemicals

Description	AP20187 (AP-20187, AP 20187) is a cell-permeable, semisynthetic bivalent ligand (dimerizer) of FK506-binding protein (FKBP F36V).
Cat.No	DC21997
Name	AP20187

Chemical Properties

CAS	195514-80-8
Formula	C82H107N5O20
MW	1482.7485
Storage	2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO

References

[1]. Ahmed S, et al. Photocleavable dimerizer for the rapid reversal of molecular trap antagonists. J Biol Chem. 2014 Feb 21;289(8):4546-52. [2]. Lin W, et al. Oligodendrocyte-specific activation of PERK signaling protects mice against experimental autoimmune encephalomyelitis. J Neurosci. 2013 Apr 3;33(14):5980-91. [3]. Haas ME, et al. The Role of Proprotein Convertase Subtilisin/Kexin Type 9 in Nephrotic Syndrome-Associated Hypercholesterolemia. Circulation. 2016 Jul 5;134(1):61-72

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