AZD5718 Datasheet DC Chemicals

Description	AZD5718 (AZD-5718, AZD 5718) is a novel potent 5-lipoxygenase activating protein (FLAP) inhibitor with binding IC50 of 6.3 nM; exhibits LTB4 inhibition in human whole blood assays with IC50 of 39 nM; reduce the production of pro-inflammatory and vasoactive leukotrienes both in vitro and in vivo.
Cat.No	DC22009
Name	AZD5718

Chemical Properties

CAS	2041075-86-7
Formula	C24H26N6O3
MW	446.511
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

References 1. Ericsson H, et al. Clin Transl Sci. 2018 May;11(3):330-338. 2. Pettersen D, et al. J Med Chem. 2019 Mar 14. doi: 10.1021/acs.jmedchem.8b02004. View Related Products by Target FLAP

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