Metarrestin Datasheet DC Chemicals
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Cat.No DC22157
Name Metarrestin

Chemical Properties

CAS 1443414-10-5
Formula C31H30N4O
MW 474.596107006073
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：1443414-10-5
Product Name：(1r,4r)-4-(7-Benzyl-4-imino-5,6-diphenyl-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-3-yl)cyclohexanol
Synonyms：trans-4-(7-Benzyl-4-imino-5,6-diphenyl-4,7-dihydro-3H-pyrr;J3.616.158B;KUC110052N;KUC109088N;KUC109037N;ML246;Q6A9F9DSX5;(1r,4r)-4-(7-benzyl-4-imino-5,6-diphenyl-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-3-yl)cyclohexanol;Metarrestin (KUC109088N);SMR002357104;MLS003678589;Metarrestin
EINEC:
Molecular Formula：C31H30N4O
Molecular Weight：474.596107006073
Target: RNA polymerase (Pol) I[1][2]
In Vivo
In Vitro
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Vilimas T, et al. Pharmacokinetic evaluation of the PNC disassembler metarrestin in wild-type and Pdx1-Cre;LSL-KrasG12D/+;Tp53R172H/+ (KPC) mice, a genetically engineered model of pancreatic cancer. Cancer Chemother Pharmacol. 2018 Dec;82(6):1067-1080. [2]. Frankowski KJ, et al. Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis. Sci Transl Med. 2018 May 16;10(441).
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