AZ-505 ditrifluoroacetate Datasheet DC Chemicals
Description AZ505 ditrifluoroacetate is a potent and selective SMYD2 inhibitor with IC50 of 0.12 μM.
Cat.No DC22293
Name AZ-505 ditrifluoroacetate

Chemical Properties

CAS 1035227-44-1
Formula C33H40CL2F6N4O8
MW 805.5891
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Komatsu S, et al. Overexpression of SMYD2 contributes to malignant outcome in gastric cancer. Br J Cancer. 2015 Jan 20;112(2):357-64. [2]. Ferguson AD, et al. Structural basis of substrate methylation and inhibition of SMYD2. Structure. 2011 Sep 7;19(9):1262-73.
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