Chemical Properties
| CAS |
2306178-56-1 |
 |
| Formula |
C21H19N3O3 |
| MW |
361.3939 |
| Storage |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Biological activity
| Description |
CAS NO.：2306178-56-1
Product Name：5-[4-(2-Methoxyethoxy)phenyl]-7-phenyl-3H-pyrrolo[2,3-d]pyrimidin-4-one
Synonyms：DMX 5084 pound>>DMX5084;BCP30841;5-(4-(2-Methoxyethoxy)phenyl)-7-phenyl-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one;5-[4-(2-Methoxyethoxy)phenyl]-7-phenyl-3H-pyrrolo[2,3-d]pyrimidin-4-one;DMX-5804
EINEC:
Molecular Formula：C21H19N3O3
Molecular Weight：361.3939 |
| Target: |
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| In Vivo |
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| In Vitro |
DMX-5804 exhibits great selectivity at MAP4K4 over other kinases, such as GCK/MAP4K2 (pIC50, 6.50), GLK/MAP4K3 (pIC50, 4.95), KHS/MAP4K5 (pIC50, 6.36), ABL1 (pIC50, 5.80), Aurora B (pIC50, 5.49), FLT3 (pIC50, 5.31), GSK3β (pIC50, 4.66), MLK1/MAP3K9 (pIC50, 7.19), MLK3/MAP3K11 (pIC50, 6.99), NUAK (pIC50, 6.88) and VEGFR (pIC50, 5.72)[1]. |
| Kinase Assay |
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| Cell Assay |
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| Animal Administration |
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References
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