TRi-1(TXNRD1 inhibitor 1) Datasheet DC Chemicals

Description	TRi-1 (TXNRD1 inhibitor 1) is a potent, specific and irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1) with anticancer potential, 5- to 10-fold higher specificity for TXNRD1 over TXNRD2.
Cat.No	DC22309
Name	TRi-1(TXNRD1 inhibitor 1)

Chemical Properties

CAS	246020-68-8
Formula	C12H9CLN2O5S
MW	328.723
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Stafford WC, et al. Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy. Sci Transl Med. 2018 Feb 14;10(428). pii: eaaf7444.

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