Cangrelor sodium Datasheet DC Chemicals
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Cat.No DC22425
Name Cangrelor sodium

Chemical Properties

CAS 163706-36-3
Formula C17H21CL2F3N5NA4O12P3S2
MW 864.29
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description
Target:
In Vivo Cangrelor tetrasodium (10 mg/kg) not only significantly decreases BLM-induced release of inflammatory cytokines (PF4, CD40 L and MPO), but also decreases the increment of platelets, neutrophils and platelet-neutrophil aggregates in the fibrotic lung and in the peripheral blood of BLM-treated mice[2].
In Vitro Cangrelor tetrasodium is the only potent intravenous direct and specific adenosine diphosphate (ADP) P2Y12 receptor antagonist[1]. Cangrelor tetrasodium has pKb of 8.6-9.2 for hP2Y12 receptor[3].
Kinase Assay
Cell Assay
Animal Administration

References

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