Leptomycin B Datasheet DC Chemicals

Description	A potent and specific nuclear export inhibitor that binds to and inhibits CRM1 (XPO1).
Cat.No	DC22444
Name	Leptomycin B

Chemical Properties

CAS	87081-35-4
Formula	C33H48O6
MW	540.730630874634
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Kudo N, et al. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region. Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):9112-7

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