Lestaurtinib Datasheet DC Chemicals
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Cat.No DC22807
Name Lestaurtinib

Chemical Properties

CAS 111358-88-4
Formula C26H21N3O4
MW 439.46
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：111358-88-4
Product Name：Lestaurtinib
Synonyms：Lestaurtinib;Lestaurtinib ( CEP-701, KT 5555, SP 924);CEP-701;CEP-701 hydrate;KT 5555;SP 924;UNII-DO989GC5D1;(15S,16S,18R)-16-HYDROXY-16-(HYDROXYMETHYL)-15-METHYL-28-OXA-4,14,19-TRIAZAOCTACYCLO[12.11.2.1^{15,18}.0^{2,6}.0^{7,27}.0^{8,13}.0^{19,26}.0^{20,25}]OCTACOSA-1(26),2(6),7(27),8,10,12,20,22,24-NONAEN-3-ONE;9,12-Epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one,2,3,9,10,11,12-hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-, [9S-(9a,10b,12a)]-;A 154475.0;CEP 701;SPM-924;Apalutamide;KT-5555 hydrate;Lestaurtinib hydrate
EINECS:
Molecular Formula：C26H21N3O4
Molecular Weight：439.46
Target: JAK2:0.9 nM (IC50) TrkA:25 nM (IC50) FLT3:3 nM (IC50)
In Vivo
In Vitro
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Miknyoczki SJ, et al. The novel Trk receptor tyrosine kinase inhibitor CEP-701 (KT-5555) exhibits antitumor efficacy against human pancreatic carcinoma (Panc1) xenograft growth and in vivo invasiveness. Ann N Y Acad Sci. 1999 Jun 30;880:252-62.
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