FB23-2(FTO Demethylase inhibitor FB23-2) Datasheet DC Chemicals

Description	FB23-2 is a potent, selective inhibitor of the mRNA N 6-methyladenosine (m 6A) demethylase FTO, directly bind to FTO, inhibits FTO demethylation of m6 A in RNA in vitro with IC50 of 2.6 uM.
Cat.No	DC23119
Name	FB23-2(FTO Demethylase inhibitor FB23-2)

Chemical Properties

CAS	2243736-45-8
Formula	C18H15CL2N3O3
MW	392.236
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Huang Y, et al. Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia. Cancer Cell. 2019 Apr 15;35(4):677-691.e10.

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