Bax inhibitor peptide V5 Datasheet DC Chemicals
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Cat.No DC23206
Name Bax inhibitor peptide V5

Chemical Properties

CAS 579492-81-2
Formula C27H50N6O6S
MW 586.7875
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description
Target:
In Vivo V5 (100 μM) significantly improves islet function following isolation and improves islet graft function following transplantation in mice model[2].
In Vitro Bax inhibitor peptide V5 (0-50 μM) reduces cell death in STF-cMyc cells but not in SW620 or NCI-H23 cells. BIPV5 does not result in any significant effect on cell cycle arrest at the G2/M phase[1]. V5 treatment upregulates expression of anti-apoptotic proteins Bcl-2 and XIAP by more than 3- and 11-fold and downregulates expression of apoptosis-inducing proteins Bax, Bad, and nuclear factor-κB-p65 by 10, 30, and nearly 50%, respectively[2].
Kinase Assay
Cell Assay
Animal Administration

References

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