PF-3450074 Datasheet DC Chemicals

Description	PF-3450074 (PF74) is a small molecule HIV capsid protein, destabilized the viral capsid in vitro.
Cat.No	DC23267
Name	PF-3450074

Chemical Properties

CAS	1352879-65-2
Formula	C₂₇H₂₇N₃O₂
MW	425.52
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Xu JP, et al. Exploring Modifications of an HIV-1 Capsid Inhibitor: Design, Synthesis, and Mechanism of Action.J Drug Des Res. 2018;5(2). pii: 1070. Epub 2018 Aug 13. [2]. Shi J, et al. Small-molecule inhibition of human immunodeficiency virus type 1 infection by virus capsid destabilization.J Virol. 2011 Jan;85(1):542-9.

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