Vacuolin-1 Datasheet DC Chemicals
Description A potent PIKfyve inhibitor that inhibits autophagy by impairing lysosomal maturation, potently and reversibly inhibits autophagosome-lysosome fusion by activating RAB5A.
Cat.No DC23322
Name Vacuolin-1

Chemical Properties

CAS 351986-85-1
Formula C26H24IN7O
MW 577.42
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

References 1. Cerny J, et al. EMBO Rep. 2004 Sep;5(9):883-8. 2. Shaik GM, et al. Cell Signal. 2009 Aug;21(8):1337-45. 3. Lu Y, et al. Autophagy. 2014;10(11):1895-905. 4. Sano O, et al. FEBS Lett. 2016 Jun;590(11):1576-85. View Related Products by Target Autophagy
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