PF-0346275 Datasheet DC Chemicals

Description	PF-0346275 is a potent, selective, orally available GlyT1 inhibitor with Ki of 11.6 nM, without activity against GlyT2 (IC50>10 uM).
Cat.No	DC23599
Name	PF-0346275

Chemical Properties

CAS	1173239-39-8
Formula	C19H22CLFN4O
MW	376.86
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

References 1. Lowe JA 3rd, et al. Bioorg Med Chem Lett. 2009 Jun 1;19(11):2974-6. 2. Yamamoto S, et al. Chem Pharm Bull (Tokyo). 2016;64(11):1630-1640. View Related Products by Target Glycine Transporter (GlyT)

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