Rheb inhibitor NR1 Datasheet DC Chemicals

Description	Rheb inhibitor NR1 is a small molecule that binds Rheb in the switch II domain (IC50=2.1 uM, Kd=1.5 uM) and selectively blocks mTORC1 signaling, potently inhibits mTORC1 driven phosphorylation of S6K1 but does not inhibit phosphorylation of AKT or ERK.
Cat.No	DC23734
Name	Rheb inhibitor NR1

Chemical Properties

CAS	2216763-38-9
Formula	C25H19BRCL2N2O3S
MW	578.304962396622
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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