ML359 Datasheet DC Chemicals

Description	ML359 is a small molecule, specific inhibitor of Protein disulfide isomerase (PDI) with IC50 of 250 nM; displays >100-fold selectivity over other thiol isomerases (Erp5, Thioredoxin, Thioredoxin reductase); shows no cytotoxicity in three human cell lines, and some activity in inhibiting platelet aggregation in vitro.
Cat.No	DC23760
Name	ML359

Chemical Properties

CAS	1069858-99-6
Formula	C19H18N4O3
MW	350.371223926544
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

References 1. Khodier C, et al. Probe Reports from the NIH Molecular Libraries Program [Internet]. View Related Products by Target Protein Disulfide Isomerase (PDI)

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