PDI inhibitor 16F16 Datasheet DC Chemicals

Description	PDI inhibitor 16F16 is a protein disulfide isomerase (PDI) inhibitor, first identified in a screen for compounds that prevent apoptosis induced by mutant huntingtin protein. 16F16 not only suppressed apoptosis induced by the misfolded protein mutant hungtingtin, it also protected rat neurons from cell death triggered by Aβ peptide. The actions of this inhibitor helped to identify a new mechanism in which a cell death pathway is regulated by protein misfolding via PDI upregulation.
Cat.No	DC23762
Name	PDI inhibitor 16F16

Chemical Properties

CAS	922507-80-0
Formula	C16H17CLN2O3
MW	320.770783185959
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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