NSC 658497 Datasheet DC Chemicals
Description NSC 658497 is a small molecule inhibitor of Ras GEF, SOS1, binds to SOS1 with Kd of 7 uM but no H-Ras, competitively suppresses SOS1-Ras interaction, and dose-dependently inhibits SOS1 GEF activity.
Cat.No DC23822
Name NSC 658497

Chemical Properties

CAS 909197-38-2
Formula C20H10N2O6S2
MW 438.428
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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