Thymalfasin Datasheet DC Chemicals
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Cat.No DC23914
Name Thymalfasin

Chemical Properties

CAS 62304-98-7
Formula C129H215N33O55
MW 3108.3
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：62304-98-7
Product Name：Thymalfasin
Synonyms：Thymosin alpha 1;ACETYL-SER-ASP-ALA-ALA-VAL-ASP-THR-SER-SER-GLU-ILE-THR-THR-LYS-ASP-LEU-LYS-GLU-LYS-LYS-GLU-VAL-VAL-GLU-GLU-ALA-GLU-ASN;AC-SDAAVDTSSEITTKDLKEKKEVVEEAEN;AC-SER-ASP-ALA-ALA-VAL-ASP-THR-SER-SER-GLU-ILE-THR-THR-LYS-ASP-LEU-LYS-GLU-LYS-LYS-GLU-VAL-VAL-GLU-GLU-ALA-GLU-ASN;AC-SER-ASP-ALA-ALA-VAL-ASP-THR-SER-SER-GLU-ILE-THR-THR-LYS-ASP-LEU-LYS-GLU-LYS-LYS-GLU-VAL-VAL-GLU-GLU-ALA-GLU-ASN-OH;THYMOSIN A1;THYMOSIN A1 BOVINE;THYMOSIN ALPHA1 BOVINE;Thymosin alpha-1;Thymosin α₁;Thymosin α1 Acetate;Thymosin α1 bovine;Thymosin-1;Thymosinα1;Thymosin ?1;Thymosin Alpha1 Acetate;THYMOSIN APHA 1;Thymosina1Acetate;ZADAXIN;Thymosina1 (ox);L-Asparagine,N-acetyl-L-seryl-L-a-aspartyl-L-alanyl-L-alanyl-L-valyl-L-a-aspartyl-L-threonyl-L-seryl-L-seryl-L-a-glutamyl-L-isoleucyl-L-threonyl-L-threonyl-L-lysyl-L-a-aspartyl-L-leucyl-L-lysyl-L-a-glutamyl-L-lysyl-L-lysyl-L-a-glutamyl-L-valyl-L-valyl-L-a-glutamyl-L-a-glutamyl-L-alanyl-L-a-glutamyl-;Thymosina1 (human);thymosin а1;N-Acetyl-L-seryl-L-alpha-aspartyl-L-alanyl-L-alanyl-L-valyl-L-alpha-aspartyl-L-threonyl-L-seryl-L-seryl-L-alpha-glutamyl-L-isoleucyl-L-threonyl-L-threonyl-L-lysyl-L-alpha-aspartyl-L-leucyl-L-lysyl-L-alpha-glutamyl-L-lysyl-L-lysyl-L-alpha-glutamyl-L-valyl-L-valyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alanyl-L-alpha-glutamyl-L-asparagine;Thymosin alpha impurity;Thymalfasin
EINEC:
Molecular Formula：C129H215N33O55
Molecular Weight：3108.3
Target:
In Vivo Thymalfasin has been shown to have efficacy in multiple experimental models of immune dysfunction, mainly, infectious diseases such as hepatitis (woodchuck) and influenza (mouse), and cancer such as melanoma (mouse) and colorectal carcinoma (rat) where thymalfasin has shown antitumor effects[2].
In Vitro Thymalfasin has been shown to have efficacy in multiple experimental models of immune dysfunction, mainly, infectious diseases such as hepatitis (woodchuck) and influenza (mouse), and cancer such as melanoma (mouse) and colorectal carcinoma (rat) where thymalfasin has shown antitumor effects[2].
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Lao X et al. A modified thymosin alpha 1 inhibits the growth of breast cancer both in vitro and in vivo: suppressment of cell proliferation, inducible cell apoptosis and enhancement of targeted anticancer effects. Apoptosis. 2015 Oct;20(10):1307-20. [2]. Sjogren MH et al. Thymalfasin: an immune system enhancer for the treatment of liver disease. J Gastroenterol Hepatol. 2004 Dec;19(12):S69-72
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