Eperezolid Datasheet DC Chemicals
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Cat.No DC24008
Name Eperezolid

Chemical Properties

CAS 165800-04-4
Formula C18H23FN4O5
MW 394.3974
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description
Target: IC50 value: 1-4 mg/ml (MIC90, staphylococci) [1] Target: Antibiotic
In Vivo
In Vitro
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Rybak MJ, et al. Comparative in vitro activities and postantibiotic effects of the oxazolidinone compounds eperezolid (PNU-100592) and linezolid (PNU-100766) versus vancomycin against Staphylococcus aureus, coagulase-negative staphylococci, Enterococcus f [2]. Lin AH, et al. The oxazolidinone eperezolid binds to the 50S ribosomal subunit and competes with binding of chloramphenicol and lincomycin. Antimicrob Agents Chemother. 1997 Oct;41(10):2127-31. [3]. Zhou CC, et al. 1H nuclear magnetic resonance study of oxazolidinone binding to bacterial ribosomes. Antimicrob Agents Chemother. 2002 Mar;46(3):625-9.
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