AVL-292 besylate Datasheet DC Chemicals
Description AVL-292 besylate (Spebrutinib, CC-292) is a highly selective, covalent Btk inhibitor with IC50 of <1 nM.
Cat.No DC24068
Name AVL-292 besylate

Chemical Properties

CAS 1360053-81-1
Formula C28H28FN5O6S
MW 581.6152
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Evans EK, et al. Inhibition of Btk with CC-292 provides early pharmacodynamic assessment of activity in mice and humans. J Pharmacol Exp Ther. 2013 Aug;346(2):219-28.
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