TH-287 hydrochloride Datasheet DC Chemicals
Description TH287 hydrochloride is a potent and selective inhibitor of MTH1, with an IC50 of 0.8 nM. TH287 hydrochloride is highly selective towards MTH1, with no relevant inhibition of MTH2, NUDT5, NUDT12, NUDT14, NUDT16, dCTPase, dUTPase and ITPA at 100 μM. TH287 hydrochloride could act as a chemotherapeutic agent for cancer research.
Cat.No DC24091
Name TH-287 hydrochloride

Chemical Properties

CAS 1638211-05-8
Formula C11H11CL3N4
MW 305.5908
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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