N-piperidine Ibrutinib hydrochloride Datasheet DC Chemicals

Description	N-piperidine Ibrutinib hydrochloride (Compound 1) is a reversible Ibrutinib derivative. N-piperidine Ibrutinib hydrochloride is a potent BTK inhibitor with IC50s of 51.0 and 30.7 nM for WT BTK and C481S BTK, respectively. N-piperidine Ibrutinib hydrochloride can be used as a BTK ligand in the synthesis of a series of PROTACs, such as SJF620. SJF620 is a potent PROTAC BTK degrader with a DC50 of 7.9 nM.
Cat.No	DC40447
Name	N-piperidine Ibrutinib hydrochloride

Chemical Properties

CAS	2231747-18-3
Formula	C22H23CLN6O
MW	422.9106
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

References

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