3-Mercaptopropionic acid NHS ester Datasheet DC Chemicals
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Cat.No DC40841
Name 3-Mercaptopropionic acid NHS ester

Chemical Properties

CAS 117235-10-6
Formula C7H9NO4S
MW 203.215660810471
Storage Pure form-20°C3 years4°C2 yearsIn solvent-80°C6 months-20°C1 month

Biological activity

Description CAS NO.：117235-10-6
Product Name：3-mercapto-Propanoic acid 2,5-dioxo-1-pyrrolidinyl ester
Synonyms：3-mercapto-Propanoic acid 2,5-dioxo-1-pyrrolidinyl ester;(2,5-dioxopyrrolidin-1-yl) 3-sulfanylpropanoate;1-(3-mercapto-1-oxopropoxy)-2,5-Pyrrolidinedione;2,5-PYRROLIDINEDIONE, 1-(3-MERCAPTO-1-OXOPROPOXY)-
EINEC:
Molecular Formula：C7H9NO4S
Molecular Weight：203.215660810471
Target: Alkyl/ether
In Vivo
In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]
Kinase Assay
Cell Assay
Animal Administration

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
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