2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Biological activity
Description
CAS NO.：1029890-89-8 Product Name：1-(4R,5R)-4,5-Dihydroxy-L-ornithine-Echinocandin B Hydrochloride Synonyms：ECBN;ECBN HCL;Echinocandin B nucleus hydrochloride;1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]echinocandin B hydrochloride;1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]echinocandin B hydrochloride (1;1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]echinocandin B hydrochloride (1:1) EINEC: Molecular Formula：C34H52CLN7O15 Molecular Weight：834.3
Target:
In Vivo
In Vitro
Echinocandin B (ECB), obtained by the fermentation of Aspergillus nidulans and Aspergillus rugulosus, is known as one of the natural cyclic hexapeptides that have a linoleoyl side chain, which inhibits a crucial enzyme in fungal cell wall biosynthesis, β-(1,3)-D-glucan synthase[1].
Kinase Assay
Cell Assay
Animal Administration
References
[1]. Lei Shao, et al. Efficient bioconversion of echinocandin B to its nucleus by overexpression of deacylase genes in different host strains. Appl Environ Microbiol. 2013 Feb;79(4):1126-33.
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