MK-8719 Datasheet DC Chemicals

Description	MK-8719 is a highly potent and selective OGA inhibitor (EC50 = 52.7 nM) which is a Potential Treatment for Tauopathies. MK-8719 showed excellent CNS penetration that has been advanced to first-in-human phase I clinical trials.
Cat.No	DC60003
Name	MK-8719

Chemical Properties

CAS	1382799-40-7
Formula	C9H14F2N2O3S
MW	268.2788
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO Application

References

[1]. Selnick HG, et al. Discovery of MK-8719, a Potent O-GlcNAcase Inhibitor as a Potential Treatment for Tauopathies. J Med Chem. 2019 Sep 29.

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