Capmatinib hydrochloride Datasheet DC Chemicals

Description	Capmatinib, also known as INCB28060 and INC280, is an orally bioavailable inhibitor of the proto-oncogene c-Met with potential antineoplastic activity. c-Met inhibitor INC280 selectively binds to c-Met, thereby inhibiting c-Met phosphorylation and disrupting c-Met signal transduction pathways. This may induce cell death in tumor cells overexpressing c-Met protein or expressing constitutively activated c-Met protein. Capmatinib was approved in 2020.
Cat.No	DC60059
Name	Capmatinib hydrochloride

Chemical Properties

CAS	1865733-40-9
Formula	C23H21CL2FN6O2
MW	503.356245756149
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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