K-Ras G12C-IN-4 Datasheet DC Chemicals
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Cat.No DC60196
Name K-Ras G12C-IN-4

Chemical Properties

CAS 2376328-55-9
Formula C31H33CLN4O4
MW 561.07
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：2376328-55-9
Product Name：K-Ras G12C-IN-4
Synonyms：K-Ras G12C-IN-4
EINECS:
Molecular Formula：C31H33ClN4O4
Molecular Weight：561.07
Target:
In Vivo
In Vitro K-Ras G12C-IN-4 (4 hours) exhibits IC50=0.219 μM for inhibition of MAPK signaling (p-ERK) in MIA PaCa-2 cells[1]. K-Ras G12C-IN-4 (72 hours) translates to a 0.067 μM IC50 for inhibition of cellular viability in a CellTiter-Glo experiment in MIA PaCa-2 cells[1].
Kinase Assay
Cell Assay
Animal Administration

References

K-Ras G12C-IN-4 (4 hours) exhibits IC50=0.219 μM for inhibition of MAPK signaling (p-ERK) in MIA PaCa-2 cells[1]. K-Ras G12C-IN-4 (72 hours) translates to a 0.067 μM IC50 for inhibition of cellular viability in a CellTiter-Glo experiment in MIA PaCa-2 cells[1].
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