TRPM4-IN-2 Datasheet DC Chemicals
Target Home > Products > Featured products
Cat.No DC60304
Name TRPM4-IN-2

Chemical Properties

CAS 667411-04-3
Formula C19H14CLNO4
MW 355.77
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：667411-04-3
Product Name：TRPM4-IN-2
Synonyms：Benzoic acid, 4-chloro-2-[[2-(1-naphthalenyloxy)acetyl]amino]-;TRPM4-IN-2
EINEC:
Molecular Formula：C19H14CLNO4
Molecular Weight：355.77
Target: TRPM4:0.16 μM (IC50)
In Vivo
In Vitro TRPM4-IN-2 (NBA) (50 μM; 0-500 s) blocks the endogenous TRPM4 currents in DU145[1]. Cell Proliferation Assay[1] Cell Line: DU145 Concentration: 50 μM Incubation Time: 0-500 s Result: Blocked 88 ± 9% of the endogenous TRPM4 currents at 50 μM.
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Borgström A, et al. Small Molecular Inhibitors Block TRPM4 Currents in Prostate Cancer Cells, with Limited Impact on Cancer Hallmark Functions. J Mol Biol. 2021 Aug 20;433(17):166665. [2]. Stokłosa P, et al. Investigation of Novel Small Molecular TRPM4 Inhibitors in Colorectal Cancer Cells. Cancers (Basel). 2021 Oct 28;13(21):5400.
Return Policy
If you are in any way unsatisfied with your purchase, you may return any item(s) within 365 days of its original purchase date.
Please provide your Order Number in the email. We strive to reply to all email inquiries within one business day.
Tel: +86-21-58447131
Fax: +86-21-61642470

Email:
sales@dcchemicals.com
order@dcchemicals.com

Website:
www.dcchemicals.com