Belumosudil mesylate Datasheet DC Chemicals
Description Belumosudil, also known as KD-025 and WHO11343, is an orally bioavailable inhibitor of ROCK-II that is greater than 200-fold selective over ROCK-I (IC50s = 105 nM and 24 µM, respectively). Belumosudil (SLx-2119; 40 µM) induces significant down-regulations of Tsp-1 and CTGF mRNA levels in PASMC.
Cat.No DC60435
Name Belumosudil mesylate

Chemical Properties

CAS 2109704-99-4
Formula C27H28N6O5S
MW 548.6134
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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