SRD5A1-IN-1 Datasheet DC Chemicals
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Cat.No DC65487
Name SRD5A1-IN-1

Chemical Properties

CAS 2279077-93-7
Formula C17H11F6NO3
MW 391.26
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：2279077-93-7
Product Name：SRD5A1-IN-1
Synonyms：
EINECS:
Molecular Formula：C17H11F6NO3
Molecular Weight：391.26
Target: IC50: 1.44 µM (SRD5A1)[1]
In Vivo
In Vitro SRD5A1-IN-1 (Compound 4) (0.5-2.5 μM; 24 h) decreases SRD5A1 protein expression[1]. SRD5A1-IN-1 (0-2.5 μM; 12 h) modulates SRD5A1 via the dual actions that affect the level of SRD5A1 protein expression and the activity of the SRD5A1 enzyme[1].
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Lin A C K, et al. Caffeic acid N-[3, 5-bis (trifluoromethyl) phenyl] amide as a non-steroidal inhibitor for steroid 5α-reductase type 1 using a human keratinocyte cell-based assay and molecular dynamics. Scientific Reports, 2022, 12(1): 1-20.
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