UNC8153 TFA Datasheet DC Chemicals
Description UNC8153 TFA is a potent and selective nuclear receptor-binding SET domain-containing 2 (NSD2)-targeted degrader with a Kd of 24 nM. UNC8153 TFA reduces the cellular levels of both NSD2 protein and the H3K36me2 chromatin mark. UNC8153 TFA contains a simple warhead that confers proteasome-dependent degradation of NSD2.
Cat.No DC66542
Name UNC8153 TFA

Chemical Properties

CAS 2929304-61-8
Formula C35H38F3N5O7
MW 697.700739383698
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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